CAR-T-cell therapies

The CAR T cell therapies tisagenlecleucel (Kymriah®) and axicabtagene ciloleucel (Yescarta®) are provisionally listed in Appendix 1 of the Health Insurance Benefits Ordinance, and are reimbursed by Swiss mandatory health insurance for the treatment of diffuse large B cell lymphoma (DLBCL; Kymriah® and Yescarta®), B cell acute lymphocytic leukaemia (ALL;  Kymriah®) and primary mediastinal B cell lymphoma (PMBCL; Yescarta®). To inform future reimbursement decision an HTA will be conducted with the aim of evaluating the safety, efficacy/effectiveness, costs, cost-effectiveness and budget impact of tisagenlecleucel and axicabtagene ciloleucel separately in these indications. In addition, ethical, legal, social and organisational issues associated with these therapies will be investigated.

Last modification 16.06.2023

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