Scoping reports

The scoping report defines the research question in concrete terms and develops the methodology for the assessment.

The scoping reports that have been completed are shown below.


The FOPH prepares a pre-scope in the form of an initial analysis and a precise definition of the questions asked in relation to the selected theme. On this basis the contractor drafts the actual scoping report. This is submitted to a group of reviewers consisting offour to five independent experts who assess the scientific quality of the report. The report is then submitted to stakeholders and finalised.

Statins in the primary prevention of cardiovascular events and mortality in Switzerland

The aim of the scoping report is to determine the feasibility of a Health Technology Assessment (HTA) report on statins in the primary prevention of cardiovascular events and mortality in Switzerland. This is in response to the identified quantity and quality of the primary literature.
The HTA report will review the efficacy, safety, cost efficiency and budgetary impact of statin treatment in adults with no proven cardiovascular disease and with a low, moderate or high cardiovascular risk compared with no treatment and/or a change in lifestyle. Its basis for doing so will be the scoping report.

Vertebroplasty or Kyphoplasty in Patients with Symptomatic, Osteoporotic Vertebral Compression Fractures

The objective of this HTA is the evaluation of the efficacy/effectiveness, safety, costs, effectiveness and budget impact of percutaneous vertebroplasty and percutaneous balloon kyphoplasty in patients with symptomatic osteoporotic vertebral compression fractures unresponsive to non-surgical treatment.

Olmesartan Mono- and Combination Therapies in Patients with Essential Hypertension

The aim of the Health Technology Assessment (HTA) is to evaluate the efficacy, effectiveness, safety, cost-effectiveness and budget impact of olmesartan mono- and combination therapies compared to all other sartan mono- and combination therapies available in Switzerland in patients with essential hypertension.

Treatment of non-erosive gastroesophageal reflux disease patients with proton pump inhibitors

The aim of the Health Technology Assessment (HTA) is to evaluate the efficacy, effectiveness, safety, cost-effectiveness and budget impact of long-term continuous proton pump inhibitor (PPI) therapy compared to long-term on-demand PPI therapy in patients with non-erosive reflux disease (NERD) and patients with uninvestigated gastroesophageal reflux disease (GERD).  

Chondroitin Sulfate in Osteoarthritis

The objective of the HTA is to compare the safety, efficacy and effectiveness of chondroitin sulfate with placebo, on-demand analgesics and anti-inflammatory treatments in patients with osteoarthritis of the hands, knees and hips. In addition, the cost-effectiveness and budgetary impact of chondroitin sulfate warrants investigation.

Removal of osteosynthesis devices (e.g. screws, plates, nails and wires) used to treat bone fractures

Research questions: How does the removal of osteosynthesis material in patients without medical indication (elective or routine removal) affect complication rates, clinical outcomes, health-related quality of life and cost-effectiveness outcomes compared to retention of the osteosynthesis material?

Self-measurement of blood glucose in patients with non-insulin treated diabetes mellitus type 2

Research questions:

  • How does a decrease in HbA1c levels affect clinical endpoints?
  • What is the safety profile of self-measurement of blood glucose?
  • What is the cost-effectiveness of the different possible variations in self-measurement of blood glucose?

Knee arthroscopy for the treatment of degenerative changes

Research question: What is the benefit of knee arthroscopy for patients with symptoms resulting from degenerative changes of the knee in general compared with non-invasive forms of therapy?

Iron replacement therapy for iron deficiency without anaemia


  1. The connection between iron deficiency without anaemia and non-haematological clinical disorders
  2. Therapeutic need for and efficacy of iron replacement therapy for iron deficiency without anaemia

Last modification 20.05.2020

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